Your Health and Shire
This site is not intended for healthcare professionals
Shire in Canada focuses on attention deficit hyperactivity disorder (ADHD),
human genetic therapies, diabetic foot ulcers (DFUs) as well as gastrointestinal and renal diseases.
Attention Deficit Hyperactivity Disorder (ADHD)
ADHD is a neurobiological disorder which affects approximately 5 to 12 per cent
of the population. Although often regarded as a childhood problem, up to 66 per
cent of children with ADHD still exhibit symptoms into adulthood.
For more information on ADHD
Ulcerative colitis, a gastrointestinal disease, is a chronic immune disorder of
the large intestine (colon). The disease is marked by inflammation and
ulcerations of the innermost lining of the intestine, called the colon mucosa.
Ulcerative Colitis always starts in the rectum and may extend as a continuous
inflammation from there into the rest of the colon.
For more information on
The kidneys act as sophisticated filters for the body. They clean and purify the
blood, sifting out waste products and excess fluid that eventually leave the
body as urine.
For more information on Kidney Disease
Diabetic Foot Ulcers
Diabetic foot ulcers (DFUs) are wounds that can develop on the foot of
people with diabetes. They are often difficult to heal and may become
chronic in nature. Several factors contribute to the development of DFUs
including peripheral neuropathy (loss of feeling in the lower extremities
resulting from nerve damage), peripheral arterial disease (circulatory
problem in which narrowed arteries reduce blood flow to the lower
extremities) and poor control of blood glucose.1 (Boulton, 2008)
Fabry disease is a rare hereditary disorder and one of a group of more than 40
disorders called lysosomal diseases. Lysosomes are a part of the cell in which
particular waste products are broken down into simpler components that can be
reused by the body. Lysosomes can be seen as one of the body’s "recycling
plants" for keeping us healthy.
For more information on Fabry Disease
Gaucher Disease is an inherited disorder, and the most common of the
lysosomal storage diseases, wherein a fatty lipid substance is not properly
broken down by the body and accumulates in various cells and organs including
the liver, spleen and bone. For more
information on Gaucher Disease
Hunter syndrome is a very rare, progressive and life threatening disease that
primarily affects males. it is one of several related lysosomal storage
For more information on Hunter Syndrome
- Boulton AJM, Armstrong DG, Frykberg RB, et al.
Comprehensive foot examination and risk assessment. Diabetes Care